AdvancedRun

For a while now, Windows has been offering its users sufficient methods of running apps by enabling them to tweak settings like system compatibility modes and others related to basic video.
If you want more, you are left with two obvious options: if you have the necessary skills, you can practice some advanced computer ninja moves using the Command Prompt or turn to a software solution that expands your OS' capabilities for running apps, such as AdvancedRun.
This is a pragmatic and useful piece of software that allows you to run programs with different and more advanced settings than you usually could.

Advanced settings to run apps, within a simplistic window

The application is not designed to win any beauty contests, but it does feature a straightforward user interface with a single window, which makes it somewhat accessible even for the most inexperienced users out there.
As expected, the utility enables you to run any app using specific environment variables, command-line arguments and it even helps you choose the start directory for the program. You can also set affinity masks and appoint the exact core of your computer's CPU that the current program should use.

Priority classes and system compatibility modes settings at your disposal

No surprise here, as AdvancedRun makes it possible for you to run apps in Normal, Idle, High, RealTime, Below Normal and Above Normal priority modes.
In addition, you can set the program's main window state (Normal, Hidden or Maximized and Minimized), as well as its window position and its default size, considering that the app offers you these options to begin with.
Furthermore, you can run apps in compatibility modes for older versions of Windows, with different users and permissions. What is more, you can disable visual themes and desktop composition, run apps in 640x480 resolution, turn off display scaling on high DPI settings and many others.

Run apps with your custom settings with just a few mouse clicks

You can save all your favorite settings into a configuration file to a location of your choosing and then easily run the program automatically with everything tailored to your needs and preferences.
All in all, if you are looking for a lightweight and simple-to-use tool that offers you more options to run your apps than Windows, then AdvancedRun might just be it.