MPMileage

Batch calculate route distances, travel times, and/or estimated costs for point-to-point routes listed in a database (Access, Excel, or ODBC). Uses Microsoft MapPoint for point locations and route calculations. Supports all of MapPoint's route options including fastest routes, shortest routes, preferred roads, and straight lines (Great Circles). Road speeds/etc can also be set. Supports all versions of MapPoint from MapPoint 2002 to the latest MapPoint 2010. The database can be any version of Access or Excel v2003 onwards. Access or an ODBC database is recommended for speed. ODBC support includes runtime login credentials, and all three kinds of Data Source Names (DSNs): User DSNs, System DSNs, and File DSNs. Supports Windows XP, Windows Vista, and Windows 7. Also supports multi-core machines: Run on a quad core (or better) for huge speeds up over conventional MapPoint batch calculation tools.
Single licenses cost US$75, and there is a free 14 day trial.