USB Drive Disabler

USB Drive Disabler is a lightweight application that can disable access to all USB ports on your computer. It is very simple to use, as it doesn't include any configuration parameters.
The app does not contain a setup pack, so you can drop the executable file anywhere on the hard disk to run it directly. Alternatively, you can run USB Drive Disabler on any workstation with minimum effort, as long as you have administrative rights.
An important aspect to take into account is that the Windows Registry does not get entry updates, and leftover files are not kept on the hard disk after removing the utility.
The interface is based on a single window where you can immediately disable all USB ports with the simple click of a button. Restoring their status is done in a similar manner, by selecting the "Enable USB Drives" option.
The program automatically exits after applying a setting. Contrary to what its description says, it is not necessary to reboot the system to implement the new modifications. However, they do not apply for USB drives already plugged into the unit (you have to re-insert them).
USB Drive Disabler immediately carries out the task while using low CPU and RAM, so it doesn't disrupt normal activity or slow down computer performance. We have not encountered any issues throughout our evaluation, as the utility did not hang or crash. However, USB Drive Disabler has not been updated for a very long time.