Portable Trillian (For U3)

Trillian is a fully featured, stand-alone, skinnable chat client that supports AIM, ICQ, MSN, Yahoo Messenger and IRC. Trillian provides capabilities not possible with original network clients, while supporting standard features such as audio chat, group chats, file transfers, buddy icons, chat rooms, multiple simultaneous connections to the same network, server-side contact importing, typing notification, direct connection (AIM), proxy support, encrypted messaging (AIM/ICQ), SMS support, and privacy settings.
Without stealing your home page and with no other included software, pop-ups, or spyware, Trillian provides unique functionality such as contact message history, a powerful skinning language, tabbed messaging, global status changes (set all networks away at once), Instant Lookup (automatic Wikipedia integration), contact alerts, an advanced automation system to trigger events based on anything happening in the client, docking, hundreds of emoticons, emotisounds, shell extensions for file transfers, and systray notifications.